Using the provided data for an average-size adult, the creatinine clearance is calculated to be approximately:

Using the provided data for an average-size adult, the creatinine clearance is calculated to be approximately:

• A. 11 mL/min
• B. 63 mL/min
• C. 95 mL/min
• D. 106 mL/min

Answer: (D)

Creatinine clearance shows how much blood the kidneys are able to clear of creatinine per minute, giving a practical sense of kidney filtering ability (a surrogate for GFR). In practice you estimate CrCl from a 24-hour urine collection or from the Cockcroft-Gault equation, which uses age, weight, sex, and serum creatinine. For an average-size adult, normal CrCl is roughly 90–120 mL/min. If the provided data lead to about 106 mL/min, that fits a normal, well-functioning kidney. The lower values (like around 11 mL/min or 63 mL/min) would indicate impaired kidney function, while a value near 95 mL/min is also near normal but the given data point aligns more closely with the 106 mL/min result. Therefore, 106 mL/min is the best approximation.

Creatinine clearance shows how much blood the kidneys are able to clear of creatinine per minute, giving a practical sense of kidney filtering ability (a surrogate for GFR). In practice you estimate CrCl from a 24-hour urine collection or from the Cockcroft-Gault equation, which uses age, weight, sex, and serum creatinine.

For an average-size adult, normal CrCl is roughly 90–120 mL/min. If the provided data lead to about 106 mL/min, that fits a normal, well-functioning kidney. The lower values (like around 11 mL/min or 63 mL/min) would indicate impaired kidney function, while a value near 95 mL/min is also near normal but the given data point aligns more closely with the 106 mL/min result. Therefore, 106 mL/min is the best approximation.