The secretion of which substance is controlled by growth hormone?

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Prepare for the Ciulla Clinical Chemistry Test with comprehensive flashcards and detailed multiple-choice questions. Each question includes helpful hints and explanations. Boost your confidence and excel in your test!

Multiple Choice

The secretion of which substance is controlled by growth hormone?

Explanation:
Growth hormone exerts its growth-promoting effects largely by stimulating the liver and other tissues to produce somatomedins, especially IGF-1 (somatomedin C). These mediators carry out the actions of GH on bones and cartilage, promoting growth. So, the substance whose secretion is driven by growth hormone is somatomedin. In contrast, a hormone that would increase GH release is growth hormone–releasing hormone, a hormone that stimulates ACTH is corticotropin-releasing hormone, and somatostatin actually inhibits GH release.

Growth hormone exerts its growth-promoting effects largely by stimulating the liver and other tissues to produce somatomedins, especially IGF-1 (somatomedin C). These mediators carry out the actions of GH on bones and cartilage, promoting growth. So, the substance whose secretion is driven by growth hormone is somatomedin. In contrast, a hormone that would increase GH release is growth hormone–releasing hormone, a hormone that stimulates ACTH is corticotropin-releasing hormone, and somatostatin actually inhibits GH release.

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