Primary aldosteronism results from a tumor of the adrenal cortex. How would the extracellular fluid be affected?

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Prepare for the Ciulla Clinical Chemistry Test with comprehensive flashcards and detailed multiple-choice questions. Each question includes helpful hints and explanations. Boost your confidence and excel in your test!

Multiple Choice

Primary aldosteronism results from a tumor of the adrenal cortex. How would the extracellular fluid be affected?

Explanation:
Excess aldosterone from an adrenal cortical tumor drives sodium reabsorption in the kidney and increases potassium excretion. Water follows sodium, so the extracellular fluid volume expands. The combined effect is more sodium in the extracellular space and less potassium due to the enhanced renal loss. So the extracellular fluid would have increased sodium and decreased potassium.

Excess aldosterone from an adrenal cortical tumor drives sodium reabsorption in the kidney and increases potassium excretion. Water follows sodium, so the extracellular fluid volume expands. The combined effect is more sodium in the extracellular space and less potassium due to the enhanced renal loss. So the extracellular fluid would have increased sodium and decreased potassium.

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